You can try some system monitoring tools to see if you spot anything, usually you might want to save changes to a loc (/var/log/logfilename.log ), whatever name you are assigned by the monitor application (if it offers to log data) or your own file name choice..http://www.informit.com/articles/article.aspx?p=770644
If it is really an odd system change you don't see, that is the cursor selection for the mouse gets changes you haven't made yourself, the normal operations of the system may not show anything you can easily detect
--therefor you need to monitor or collect data (*.logs) or look at sytsme messages, in a terminal (console) via..
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--gets the last few system events
--dmesg, some examples..