One thing I would love to hear is a feature episode on LMDE. I believe that LMDE is a really great variant of Mint. Being a self proclaimed "Linux Newbie" for the past few years, i'd like to get to know more about Debian, and how it fit's into LMDE. Also a few tips and tricks for tweaking it for better visual and overall performance would be great as well.
On a side note I've also installed Linux Mint 10 on one of my other computers, and I have to say it's by far my favorite main edition yet. I feel if LMDE could get a little more polish as far as the interface goes, I could possibly switch to just LMDE, but for the moment I'm running the two editions on a few computers just to experience something new.
Anyway, keep it up! I hope to hear more in the coming podcasts!