Thanks for your help. I managed to play yesterday, after following your advice. So, here's a summary of what settings work for me. Maybe they can help other people?
- Linux Mint 16 - Cinnamon Edition - 64 bits
- Playonlinux (with Wine 1.7.15)
- nvidia319 driver from "Driver Manager" (I own a NVIDIA GeForce 550 Ti)
- installed D3 using .exe provided by Playonlinux.
Everything seem to work, altough, sometimes in menus, game "hangs". But I managed to play almost two hours non stop yesterday. So happy
Thanks for your help!