When in doubt, check WineHQ: http://appdb.winehq.org/objectManager.p ... n&iId=2077
As for libreoffice, it's an old article, but: http://www.speakeasysolutions.com/blog/ ... l-medical/
IMO you should boot through a live CD/DVD/USB (ie. burn mint onto a medium and boot through it) and give it a go. It won't be as fast as an actual install, but you'll be able to see for yourself what works and what doesn't.
In regards to wine versioning (since the results on WineHQ vary from version to version), look at giving playonlinux a try.
PC: Manjaro/LM 13 x64 XFCE, Kernel 3.11.1-6/3.8.0-32-generic, Nvidia GTX650, i7 3770K, 16GB RAM, Asus Xonar DX
Laptop: Lenovo G560, LM 13 x64 XFCE, Kernel 3.11.1, i3, 6GB RAMMy HTML5 login themes + screenshots