I am using an Epson 4490 in Gloria 32-bit. I don't know if this will work on x64, & I don't know if other Epson scanners will work though it seems likely that scanners from a similar Epson "family" will. The repositories are not mine, but belong to DoctorMo, & member of the Ubuntu forums that helped me get my 4490 working in Ubuntu. The process is slightly different for Mint.
MENU > PACKET MANAGER > SETTINGS > REPOSITORIES
Add the following two lines as seen here in my screenshot:
Open up a terminal & run the following command:
sudo apt-get install iscan iscan-plugins
Restart your computer & turn on your scanner. Now go to MENU > GRAPHICS > Image Scan! & you should see a similar screen.