Slackware is good, but I've never tried wine on it. Slack is great - either_32 or _64. I've used Pardus for nearly 2 years, and it is neat and slick - rolling distro of sorts. You can install 2009.2 and wait for the upgrade, which should be painless, as in the past. Or, you can install 2011 now. Pardus 2011 has a 64 bit version, and it is solid. Again, I don't use wine. You might check Phoronix to see if they have tested wine on any distros.
Both have package managers that are a bit different. Pardus Pisi has never broken any of my systems with updates/upgrades. The Deb derivatives need "protection" which is why Mint updater is so beloved. Actually, those who use it are simply not updating some critical programs, but that's another story. Course, one can always just use Debian and stay relatively safe.
Pardus 2009.2 x86_32 has a PAE kernel (with modules and headers) that actually works if you need it. Pardus repositories are a bit slim, as are Slackware. Might actually have to build from source if not in repos
"Books? Who needs books? They don't taste all that good." The American Connoisseur, circa 2010
"Radiation is good for you.Everyone should eat radiation to be fulfilled. (free translation)...Ann Coulter, circa 2011