The latest Wine version in Synaptic is version 1.3 which has been tested to integrate with LinuxMint without causing any hiccups.
The latest stable release is version 1.4.1.
Version 1.5 is a development release.
Photoshop CS5 is reported as working poorly in Wine in Linux:http://www.codeweavers.com/compatibilit ... pp_id=7715
Try CS4 which is known to work perfectly.