Yes it is sort of possible.
The problem I have discovered is because of the login manager MDM. At first I couldn't understand why using preseed used to work in earlier versions of Mint and then all of a sudden it broke. Going to MDM was the change that broke it.
My solution involves creating a custom ISO using a tweaked version of the Ubuntu Customisation Kit where you install LightDM and do some configuration changes to make it all look Minty and then you install this ISO and all is well.
If you're interested in exploring this further let me know and I'll show you how I did it. I'd be keen to know how you get the PXE and kickstart stuff working.