There is only one app that I must run before I wipe my working system, it's Photoshop CS6 which I have working under wine. Now, photoshop works but works but only works on some distros, works great in Funtoo though.
I can downgrade to CS5 if I have to, I do have a license for it.
Will Ubuntu/Mint suffice for a video/music studio environment?
Also for those that want to try Gentoo/Funtoom, it's an excellent system that does optimize but when you run crazy hardware like me you will see minimal gains where it's not noticable and a lot of the times now it matters more on drivers and if your hardware even works in linux.
Here is my specs and why source doesn't matter, TO ME, and why gentoo may just end up as my server distro and mint or ubuntu may just be on my desktop.
Intel Xeon E5-2687W Sandy Bridge-EP Overclocked @4.5GHZ
64GB of DDR3 ram @ 3200MHZ (Corsair Plat Dominator series)
PNY VCQ6000-PB Quadro 6000 6GB 384-bit X2
Sapphire Nvidia GTX Geforce 680 2GB (just bought this for gaming)
As you can see pretty crazy and pretty pricey, not for the normal joe. And I'm just not seeing performance gains.