I've been using MS wireless keyboard 6000 v2.0 and wireless mouse 5000 v1.0 without any problem. I have a dual boot system (windows 7 - linux mint).
Since I upgraded mint from 13 to 14 (tried also 14.1), keyboard and mouse don't function properly. After a few minutes or a couple of hours sometimes, both keyboard and mouse disappear. The only thing I can do is unplug the usb receiver from pc usb slot. After some time, same thing happens again.
I don't want to change my keyboard/mouse since I know that it is a mint 14 issue (both windows 7 and mint 13 work perfectly).